Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are sialylated. While macaques synthesize the sialic acid variant N-glycolylneuraminic acid (Neu5Gc), h...

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Main Authors: Dankwa, Selasi (Author), Lim, Caeul (Author), Bei, Amy K. (Author), Jiang, Rays H. Y. (Author), Abshire, James Robbins (Contributor), Patel, Saurabh D. (Author), Goldberg, Jonathan M. (Author), Moreno, Yovany (Author), Kono, Maya (Author), Niles, Jacquin C. (Contributor), Duraisingh, Manoj T. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Springer Nature, 2016-06-16T19:27:14Z.
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