Reconstructing Causal Biological Networks through Active Learning

Reconstructing Causal Biological Networks through Active Learning

Reverse-engineering of biological networks is a central problem in systems biology. The use of intervention data, such as gene knockouts or knockdowns, is typically used for teasing apart causal relationships among genes. Under time or resource constraints, one needs to carefully choose which interv...

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Bibliographic Details
Main Authors: Cho, Hyunghoon (Contributor), Berger Leighton, Bonnie (Contributor), Peng, Jian (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor), Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science (Contributor), Massachusetts Institute of Technology. Department of Mathematics (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2016-06-22T20:26:10Z.
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