Spatial signals link exit from mitosis to spindle position

Spatial signals link exit from mitosis to spindle position

In budding yeast, if the spindle becomes mispositioned, cells prevent exit from mitosis by inhibiting the mitotic exit network (MEN). The MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase Cdc14. There are two competing models that explain MEN regul...

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Bibliographic Details
Main Authors: Falk, Jill (Contributor), Tsuchiya, Dai (Author), Verdaasdonk, Jolien (Author), Lacefield, Soni (Author), Bloom, Kerry (Author), Amon, Angelika B (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Amon, Angelika B. (Contributor)
Format: Article
Language:English
Published: eLife Sciences Publications, Ltd., 2016-07-07T14:57:18Z.
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