Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression

Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression

Several functionally distinct isoforms of the actin regulatory Mena are produced by alternative splicing during tumor progression. Forced expression of the Mena[superscript INV] isoform drives invasion, intravasation and metastasis. However, the abundance and distribution of endogenously expressed M...

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Main Authors: Rohani, Nazanin (Contributor), Moufarrej, Mira N. (Contributor), Jones, Joan G. (Author), Condeelis, John S. (Author), Gertler, Frank B. (Author), Oudin, Madeleine Julie (Contributor), Gertler, Frank (Contributor), Hughes-Alford, Shannon Kay (Author), Lauffenburger, Douglas A (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Hughes, Shannon K. (Contributor), Lauffenburger, Douglas A. (Contributor)
Format: Article
Language:English
Published: Springer Netherlands, 2016-07-14T21:18:56Z.
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