Intrachromosomal homologous recombination between inverted amplicons on opposing Y-chromosome arms

Intrachromosomal homologous recombination between inverted amplicons on opposing Y-chromosome arms

Amplicons - large, nearly identical repeats in direct or inverted orientation - are abundant in the male-specific region of the human Y chromosome (MSY) and provide targets for intrachromosomal non-allelic homologous recombination (NAHR). Thus far, NAHR events resulting in deletions, duplications, i...

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Main Authors: Noordam, Michiel J. (Author), van Daalen, Saskia K. M. (Author), Skaletsky, Helen (Contributor), Clark, Brian A. (Author), Macville, Merryn V. (Author), Repping, Sjoerd (Author), Lange, Julian (Author), Page, David C (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Lange, Julian Hendrik (Contributor), Page, David C. (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-08-30T18:21:29Z.
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