Loss of G[subscript α12/13] exacerbates apical area-dependence of actomyosin contractility

Loss of G[subscript α12/13] exacerbates apical area-dependence of actomyosin contractility

During development, coordinated cell shape changes alter tissue shape. In the Drosophila ventral furrow and other epithelia, apical constriction of hundreds of epithelial cells folds the tissue. Genes in the G[subscript α12/13] pathway coordinate collective apical constriction, but the mechanism of...

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Bibliographic Details
Main Authors: Xie, Shicong (Contributor), Mason, Frank M (Contributor), Martin, Adam C (Contributor)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: American Society for Cell Biology, 2016-11-04T20:05:57Z.
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