Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases

Genome wide association studies (GWAS) provide a powerful approach for uncovering disease-associated variants in human, but fine-mapping the causal variants remains a challenge. This is partly remedied by prioritization of disease-associated variants that overlap GWAS-enriched epigenomic annotations...

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Bibliographic Details
Main Authors: Li, Yue (Contributor), Kellis, Manolis (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2016-11-04T20:46:59Z.
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