tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence

tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence

Microbial pathogens adapt to the stress of infection by regulating transcription, translation and protein modification. We report that changes in gene expression in hypoxia-induced non-replicating persistence in mycobacteria-which models tuberculous granulomas-are partly determined by a mechanism of...

Full description

Bibliographic Details
Main Authors: Chionh, Yok Hian (Contributor), McBee, Megan (Author), Babu, I. Ramesh (Contributor), Hia, Fabian (Author), Lin, Wenwei (Author), Zhao, Wei (Author), Cao, Jianshu (Contributor), Dziergowska, Agnieszka (Author), Malkiewicz, Andrzej (Author), Begley, Thomas J. (Author), Alonso, Sylvie (Author), Dedon, Peter C. (Author)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor), Singapore-MIT Alliance in Research and Technology (SMART) (Contributor), McBee, Megan E (Contributor), Dedon, Peter C (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-11-15T18:47:36Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items