Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

Targeted RNA delivery to lung endothelial cells has the potential to treat conditions that involve inflammation, such as chronic asthma and obstructive pulmonary disease. To this end, chemically modified dendrimer nanomaterials were synthesized and optimized for targeted small interfering RNA (siRNA...

Full description

Bibliographic Details
Main Authors: Barnes, Carmen M. (Author), Khan, Omar Fizal (Contributor), Zaia, Edmond (Contributor), Jhunjhunwala, Siddharth (Contributor), Xue, Wen (Contributor), Yun, Dong Soo (Contributor), Dahlman, James (Contributor), Dong, Yizhou (Contributor), Pelet, Jeisa (Contributor), Webber, Matthew (Contributor), Tsosie, Jonathan (Contributor), Jacks, Tyler E. (Contributor), Langer, Robert S. (Contributor), Anderson, Daniel Griffith (Contributor), Cai, Wenxin,M. Arch.Massachusetts Institute of Technology (Author)
Other Authors: Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Cai, Wenxin (Contributor)
Format: Article
Language:English
Published: American Chemical Society (ACS), 2016-11-17T22:44:15Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items