Paired exome analysis of Barrett's esophagus and adenocarcinoma
Barrett's esophagus, is thought to progress to esophageal adenocarcinoma (EAC) through a stepwise progression with loss of CDKN2A followed by p53 inactivation and aneuploidy. Here, we present whole exome sequencing from 25 pairs of EAC and Barrett's and five patients whose Barrett's a...
Main Authors: | Stachler, Matthew D (Author), Taylor-Weiner, Amaro (Author), Peng, Shouyong (Author), McKenna, Aaron (Author), Agoston, Agoston T (Author), Odze, Robert D (Author), Davison, Jon M (Author), Nason, Katie S (Author), Loda, Massimo (Author), Leshchiner, Ignaty (Author), Stewart, Chip (Author), Stojanov, Petar (Author), Seepo, Sara (Author), Lawrence, Michael S (Author), Ferrer-Torres, Daysha (Author), Lin, Jules (Author), Chang, Andrew C (Author), Gabriel, Stacey B (Author), Beer, David G (Author), Getz, Gad (Author), Carter, Scott L (Author), Bass, Adam J (Author), Lander, Eric Steven (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor) |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2016-11-18T15:56:08Z.
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Subjects: | |
Online Access: | Get fulltext |
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