Paired exome analysis of Barrett's esophagus and adenocarcinoma

Paired exome analysis of Barrett's esophagus and adenocarcinoma

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Barrett's esophagus, is thought to progress to esophageal adenocarcinoma (EAC) through a stepwise progression with loss of CDKN2A followed by p53 inactivation and aneuploidy. Here, we present whole exome sequencing from 25 pairs of EAC and Barrett's and five patients whose Barrett's a...

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Main Authors: Stachler, Matthew D (Author), Taylor-Weiner, Amaro (Author), Peng, Shouyong (Author), McKenna, Aaron (Author), Agoston, Agoston T (Author), Odze, Robert D (Author), Davison, Jon M (Author), Nason, Katie S (Author), Loda, Massimo (Author), Leshchiner, Ignaty (Author), Stewart, Chip (Author), Stojanov, Petar (Author), Seepo, Sara (Author), Lawrence, Michael S (Author), Ferrer-Torres, Daysha (Author), Lin, Jules (Author), Chang, Andrew C (Author), Gabriel, Stacey B (Author), Beer, David G (Author), Getz, Gad (Author), Carter, Scott L (Author), Bass, Adam J (Author), Lander, Eric Steven (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2016-11-18T15:56:08Z.
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