Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes

Biophysical changes reduce energetic demand in growth factor-deprived lymphocytes

Cytokine regulation of lymphocyte growth and proliferation is essential for matching nutrient consumption with cell state. Here, we examine how cellular biophysical changes that occur immediately after growth factor depletion promote adaptation to reduced nutrient uptake. After growth factor withdra...

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Main Authors: Kim, Dong-Hwee (Author), Wirtz, Denis (Author), Hecht, Vivian Chaya (Contributor), Sullivan, Lucas Bryan (Contributor), Kimmerling, Robert John (Contributor), Hosios, Aaron Marc (Contributor), Stockslager, Max Andrew (Contributor), Stevens, Mark M. (Contributor), Kang, Joon Ho (Contributor), Vander Heiden, Matthew G. (Contributor), Manalis, Scott R (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Massachusetts Institute of Technology. Department of Physics (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, The, 2016-11-21T16:00:37Z.
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