Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors

Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors

The delivery of diagnostic and therapeutic agents to solid tumors is limited by physical transport barriers within tumors, and such restrictions directly contribute to decreased therapeutic efficacy and the emergence of drug resistance. Nanomaterials designed to perturb the local tumor environment w...

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Bibliographic Details
Main Authors: Scherz-Shouval, R. (Author), Galie, P. A. (Author), Whitesell, L. (Author), Chen, C. S. (Author), Bagley, Alexander F (Contributor), Zhang, Angela Q. (Contributor), Wyckoff, Jeffrey (Contributor), Lindquist, Susan (Contributor), Bhatia, Sangeeta N (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: American Association for Cancer Research, 2016-11-30T16:36:40Z.
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