Essentiality of threonylcarbamoyladenosine (t[superscript 6]A), a universal tRNA modification, in bacteria

Essentiality of threonylcarbamoyladenosine (t[superscript 6]A), a universal tRNA modification, in bacteria

Threonylcarbamoyladenosine (t[superscript 6]A) is a modified nucleoside universally conserved in tRNAs in all three kingdoms of life. The recently discovered genes for t6A synthesis, including tsaC and tsaD, are essential in model prokaryotes but not essential in yeast. These genes had been identifi...

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Bibliographic Details
Main Authors: Thiaville, Patrick C. (Author), El Yacoubi, Basma (Author), Thiaville, Jennifer J. (Author), Deutsch, Chris (Author), Iwata-Reuyl, Dirk (Author), Bacusmo, Jo Marie (Author), Armengaud, Jean (Author), Bessho, Yoshitaka (Author), Wetzel, Collin (Author), Cao, Xiaoyu (Author), Limbach, Patrick A. (Author), de Crécy-Lagard, Valérie (Author), Koehrer, Caroline (Contributor), Rajbhandary, Uttam L (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2016-12-02T20:38:51Z.
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