A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation
The "cancerized field" concept posits that cancer-prone cells in a given tissue share an oncogenic mutation, but only discreet clones within the field initiate tumors. Most benign nevi carry oncogenic BRAF[superscript V600E] mutations but rarely become melanoma. The zebrafish crestin gene...
Main Authors: | , , , , , , , , , , , , , , , , , |
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Other Authors: | , , , |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS),
2016-12-19T16:29:02Z.
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Subjects: | |
Online Access: | Get fulltext |