Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity

Mediobasal hypothalamic overexpression of DEPTOR protects against high-fat diet-induced obesity

Background/Objective: The mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that functions into distinct protein complexes (mTORC1 and mTORC2) that regulate energy homeostasis. DEP-domain containing mTOR-interacting protein (DEPTOR) is part of these complexes and is known to dampen...

Full description

Bibliographic Details
Main Authors: Caron, Alexandre (Author), Labbé, Sébastien M. (Author), Lanfray, Damien (Author), Blanchard, Pierre-Gilles (Author), Villot, Romain (Author), Roy, Christian (Author), Richard, Denis (Author), Laplante, Mathieu (Author), Sabatini, David (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Elsevier, 2016-12-27T20:14:55Z.
Subjects:
Article
Online Access:Get fulltext

Internet

Get fulltext

Similar Items