Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model

Intraperitoneal delivery of paclitaxel by poly(ether-anhydride) microspheres effectively suppresses tumor growth in a murine metastatic ovarian cancer model

Intraperitoneal (IP) chemotherapy is more effective than systemic chemotherapy for treating advanced ovarian cancer, but is typically associated with severe complications due to high dose, frequent administration schedule, and use of non-biocompatible excipients/delivery vehicles. Here, we developed...

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Main Authors: Wood, Joseph (Author), Wang, Ying-Ying (Author), Zeng, Qi (Author), Simons, Brian W (Author), Fu, Jie (Author), Chuang, Chi-Mu (Author), Lai, Samuel K (Author), Wu, T.-C (Author), Hung, Chien-Fu (Author), Hanes, Justin (Author), Simons, Brian W. (Author), Lai, Samuel K. (Author), Tang, Benjamin C. (Contributor), Yang, Ming, S.M. Massachusetts Institute of Technology (Author), Yu, Tao, Ph. D. Massachusetts Institute of Technology (Author)
Other Authors: Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Springer US, 2016-12-28T20:57:42Z.
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