Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases
Since the discovery of NAD-dependent deacetylase activity of the silent information regulator-2 (SIR2) family ('sirtuins'), many exciting connections between protein deacetylation and energy metabolism have been revealed. The importance of sirtuins in the regulation of many fundamental bio...
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Format: | Article |
Language: | English |
Published: |
Elsevier,
2017-01-12T19:04:28Z.
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Online Access: | Get fulltext |