Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling

Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling

Posttranslational modifications are central to the spatial and temporal regulation of protein function. Among others, phosphorylation and ubiquitylation are known to regulate proximal T-cell receptor (TCR) signaling. Here we used a systematic and unbiased approach to uncover deubiquitylating enzymes...

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Bibliographic Details
Main Authors: Jahan, Akhee S. (Author), Lestra, Maxime (Author), Swee, Lee Kim (Author), Fan, Ying (Author), Lamers, Mart M. (Author), Tafesse, Fikadu G. (Author), Theile, Christopher S. (Author), Spooner, Eric (Author), Bruzzone, Roberto (Author), Sanyal, Sumana (Author), Ploegh, Hidde (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-01-12T20:56:28Z.
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