Membrane anchoring stabilizes and favors secretion of New Delhi metallo-β-lactamase
Carbapenems, 'last-resort' β-lactam antibiotics, are inactivated by zinc-dependent metallo-β-lactamases (MBLs). The host innate immune response withholds nutrient metal ions from microbial pathogens by releasing metal-chelating proteins such as calprotectin. We show that metal sequestratio...
| Main Authors: | , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group,
2017-01-12T21:24:40Z.
|
| Subjects: | |
| Online Access: | Get fulltext |