Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma
Follicular lymphoma is an incurable B cell malignancy characterized by the t(14;18) translocation and mutations affecting the epigenome. Although frequent gene mutations in key signaling pathways, including JAK-STAT, NOTCH and NF-κB, have also been defined, the spectrum of these mutations typically...
Main Authors: | , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2017-01-17T21:22:37Z.
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Subjects: | |
Online Access: | Get fulltext |