Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release

The SNARE-binding protein complexin (Cpx) has been demonstrated to regulate synaptic vesicle fusion. Previous studies are consistent with Cpx functioning either as a synaptic vesicle fusion clamp to prevent premature exocytosis, or as a facilitator to directly stimulate release. Here we examined con...

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Bibliographic Details
Main Authors: Cho, Richard W. (Contributor), Song, Yun (Contributor), Littleton, J. Troy (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor)
Format: Article
Language:English
Published: Elsevier B.V., 2017-01-31T15:51:37Z.
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