Comparative analysis of Drosophila and mammalian complexins as fusion clamps and facilitators of neurotransmitter release
The SNARE-binding protein complexin (Cpx) has been demonstrated to regulate synaptic vesicle fusion. Previous studies are consistent with Cpx functioning either as a synaptic vesicle fusion clamp to prevent premature exocytosis, or as a facilitator to directly stimulate release. Here we examined con...
Main Authors: | Cho, Richard W. (Contributor), Song, Yun (Contributor), Littleton, J. Troy (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences (Contributor), Picower Institute for Learning and Memory (Contributor) |
Format: | Article |
Language: | English |
Published: |
Elsevier B.V.,
2017-01-31T15:51:37Z.
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Subjects: | |
Online Access: | Get fulltext |
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