The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA

The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA

The misincorporation of 2'-deoxyribonucleotides (dNs) into RNA has important implications for the function of non-coding RNAs, the translational fidelity of coding RNAs and the mutagenic evolution of viral RNA genomes. However, quantitative appreciation for the degree to which dN misincorporati...

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Bibliographic Details
Main Authors: Wang, Jin (Author), Dong, Hongping (Author), Chionh, Yok Hian (Author), McBee, Megan E. (Author), Sirirungruang, Sasilada (Author), Cunningham, Richard P. (Author), Shi, Pei-Yong (Author), Dedon, Peter C (Contributor)
Other Authors: Massachusetts Institute of Technology. Center for Environmental Health Sciences (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor)
Format: Article
Language:English
Published: Oxford University Press, 2017-02-02T15:45:59Z.
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