Physiome-on-a-Chip: The Challenge of "Scaling" in Design, Operation, and Translation of Microphysiological Systems
Scaling of a microphysiological system (MPS) or physiome-on-a-chip is arguably two interrelated, modeling-based activities: on-platform scaling and in vitro-in vivo translation. This dual approach reduces the need to perfectly rescale and mimic in vivo physiology, an aspiration that is both extremel...
Main Authors: | Stokes, CL (Author), Lauffenburger, Douglas A (Contributor), Cirit, Murat (Contributor) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering (Contributor) |
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group,
2017-02-02T21:00:09Z.
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Subjects: | |
Online Access: | Get fulltext |
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