Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice

Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice

The transplantation of glucose-responsive, insulin-producing cells offers the potential for restoring glycemic control in individuals with diabetes. Pancreas transplantation and the infusion of cadaveric islets are currently implemented clinically, but these approaches are limited by the adverse eff...

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Main Authors: Gürtler, Mads (Author), Millman, Jeffrey R (Author), Pagliuca, Felicia W (Author), McGarrigle, James J (Author), Bochenek, Matthew A (Author), Hollister-Lock, Jennifer (Author), Oberholzer, Jose (Author), Greiner, Dale L (Author), Weir, Gordon C (Author), Melton, Douglas A (Author), Vegas, Arturo (Contributor), Veiseh, Omid (Contributor), Bader, Andrew (Contributor), Doloff, Joshua C (Contributor), Li, Jie (Contributor), Chen, Michael (Contributor), Olejnik, Karsten (Contributor), Tam, Hok Hei (Contributor), Jhunjhunwala, Siddharth (Contributor), Langan, Erin (Contributor), Aresta-Dasilva, Stephanie K (Contributor), Gandham, Srujan Kumar (Contributor), Langer, Robert S (Contributor), Anderson, Daniel Griffith (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-02-15T20:16:15Z.
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