High-throughput functional comparison of promoter and enhancer activities

Promoters initiate RNA synthesis, and enhancers stimulate promoter activity. Whether promoter and enhancer activities are encoded distinctly in DNA sequences is unknown. We measured the enhancer and promoter activities of thousands of DNA fragments transduced into mouse neurons. We focused on genomi...

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Bibliographic Details
Main Authors: Nguyen, Thomas A. (Author), Jones, Richard D. (Author), Snavely, Andrew R. (Author), Pfenning, Andreas R. (Contributor), Kirchner, Rory (Author), Hemberg, Martin (Author), Gray, Jesse M. (Author)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor)
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press, 2017-02-16T15:31:38Z.
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