Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units

Microfluidic device for the formation of optically excitable, three-dimensional, compartmentalized motor units

Motor units are the fundamental elements responsible for muscle movement. They are formed by lower motor neurons and their muscle targets, synapsed via neuromuscular junctions (NMJs). The loss of NMJs in neurodegenerative disorders (such as amyotrophic lateral sclerosis or spinal muscle atrophy) or...

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Main Authors: Platt, Randall Jeffrey (Contributor), Subramanian, Vidya (Contributor), Pearl, Taylor M. (Contributor), Rowlands, Christopher (Contributor), Chan, Vincent (Contributor), Boyer, Laurie Ann (Contributor), So, Peter T. C. (Contributor), Kamm, Roger Dale (Contributor), Uzel, Sebastien Guy Marcel (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor), Singapore-MIT Alliance in Research and Technology (SMART) (Contributor), Uzel, Sebastien GM (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2017-02-23T19:52:37Z.
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