Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines

To maintain protein homeostasis, AAA+ proteolytic machines degrade damaged and unneeded proteins in bacteria, archaea and eukaryotes. This process involves the ATP-dependent unfolding of a target protein and its subsequent translocation into a self-compartmentalized proteolytic chamber. Related AAA+...

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Bibliographic Details
Main Authors: Olivares, Adrian O. (Contributor), Baker, Tania (Contributor), Sauer, Robert T. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Sauer, Bob (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-03-17T16:24:05Z.
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