TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse

TEX11 is mutated in infertile men with azoospermia and regulates genome-wide recombination rates in mouse

Genome‐wide recombination is essential for genome stability, evolution, and speciation. Mouse Tex11, an X‐linked meiosis‐specific gene, promotes meiotic recombination and chromosomal synapsis. Here, we report that TEX11 is mutated in infertile men with non‐obstructive azoospermia and that an analogo...

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Bibliographic Details
Main Authors: Yang, Fang (Author), Silber, Sherman (Author), Leu, N. Adrian (Author), Oates, Robert D. (Author), Marszalek, Janet D. (Author), Skaletsky, Helen (Author), Brown, Laura G. (Author), Rozen, Steve (Author), Wang, P. Jeremy (Author), Page, David C (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: EMBO Press, 2017-03-27T16:08:04Z.
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