The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors

Summary - The transmembrane adaptor PAG (Cbp) has been proposed to mediate membrane recruitment of Csk, a cytoplasmic protein tyrosine kinase playing a critical inhibitory role during T cell activation, by inactivating membrane-associated Src kinases. However, this model has not been validated by ge...

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Bibliographic Details
Main Authors: Davidson, Dominique (Author), Zhong, Ming-Chao (Author), Pandolfi, Pier Paolo (Author), Bolland, Silvia (Author), Seed, Brian (Author), Li, Xin (Author), Gu, Hua (Author), Veillette, André (Author), Xavier, Ramnik Joseph (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-04-03T14:03:35Z.
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