Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

Polarization of the Effects of Autoimmune and Neurodegenerative Risk Alleles in Leukocytes

To extend our understanding of the genetic basis of human immune function and dysfunction, we performed an expression quantitative trait locus (eQTL) study of purified CD4[superscript +] T cells and monocytes, representing adaptive and innate immunity, in a multi-ethnic cohort of 461 healthy individ...

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Main Authors: Raj, T. (Author), Rothamel, K. (Author), Mostafavi, S. (Author), Ye, C. (Author), Lee, M. N. (Author), Replogle, J. M. (Author), Feng, T. (Author), Lee, M. (Author), Asinovski, N. (Author), Frohlich, I. (Author), Imboywa, S. (Author), Von Korff, A. (Author), Okada, Y. (Author), Patsopoulos, N. A. (Author), Davis, S. (Author), McCabe, C. (Author), Paik, H.-i (Author), Srivastava, G. P. (Author), Raychaudhuri, S. (Author), Hafler, D. A. (Author), Koller, D. (Author), Hacohen, N. (Author), Mathis, D. (Author), Benoist, C. (Author), Stranger, B. E. (Author), De Jager, P. L. (Author), Regev, Aviv (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2017-04-10T14:08:03Z.
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