A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer

Local recurrence is a common cause of treatment failure for patients with solid tumors. Intraoperative detection of microscopic residual cancer in the tumor bed could be used to decrease the risk of a positive surgical margin, reduce rates of reexcision, and tailor adjuvant therapy. We used a protea...

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Main Authors: Whitley, M. J. (Author), Cardona, D. M. (Author), Lazarides, A. L. (Author), Spasojevic, I. (Author), Ferrer, J. M. (Author), Lee, C.-L (Author), Snuderl, M. (Author), Blazer, D. G. (Author), Hwang, E. S. (Author), Greenup, R. A. (Author), Mosca, P. J. (Author), Mito, J. K. (Author), Cuneo, K. C. (Author), Larrier, N. A. (Author), OReilly, E. K. (Author), Riedel, R. F. (Author), Eward, W. C. (Author), Strasfeld, D. B. (Author), Fukumura, D. (Author), Lee, W. D. (Author), Kirsch, D. G. (Author), Brigman, B. E. (Author), Cahill, Joan (Author), Jain, Rakesh J. (Author), Griffith, Linda G (Contributor), Bawendi, Moungi G (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemistry (Contributor)
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS), 2017-04-14T19:48:58Z.
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