Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism

Neuroblastoma is a paediatric malignancy that typically arises in early childhood, and is derived from the developing sympathetic nervous system. Clinical phenotypes range from localized tumours with excellent outcomes to widely metastatic disease in which long-term survival is approximately 40% des...

Full description

Bibliographic Details
Main Authors: Oldridge, Derek A. (Author), Wood, Andrew C. (Author), Weichert-Leahey, Nina (Author), Crimmins, Ian (Author), Sussman, Robyn (Author), Winter, Cynthia (Author), McDaniel, Lee D. (Author), Diamond, Maura (Author), Hart, Lori S. (Author), Zhu, Shizhen (Author), Durbin, Adam D. (Author), Anders, Lars (Author), Tian, Lifeng (Author), Zhang, Shile (Author), Wei, Jun S. (Author), Khan, Javed (Author), Bramlett, Kelli (Author), Rahman, Nazneen (Author), Capasso, Mario (Author), Iolascon, Achille (Author), Gerhard, Daniela S. (Author), Guidry Auvil, Jaime M. (Author), Hakonarson, Hakon (Author), Diskin, Sharon J. (Author), Thomas Look, A. (Author), Maris, John M. (Author), Abraham, Brian Joseph (Contributor), Young, Richard A. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor), Young, Richard A (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-04-18T13:12:44Z.
Subjects:
Online Access:Get fulltext