RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression
Interleukin-17 (IL-17)-producing helper T cells (Th17 cells) play an important role in autoimmune diseases. However, not all Th17 cells induce tissue inflammation or autoimmunity. Th17 cells require IL-23 receptor (IL-23R) signaling to become pathogenic. The transcriptional mechanisms controlling th...
Main Authors: | , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
Elsevier,
2017-04-18T20:30:56Z.
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Subjects: | |
Online Access: | Get fulltext |