Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers

Massively parallel sequencing of single cells by epicPCR links functional genes with phylogenetic markers

Many microbial communities are characterized by high genetic diversity. 16S ribosomal RNA sequencing can determine community members, and metagenomics can determine the functional diversity, but resolving the functional role of individual cells in high throughput remains an unsolved challenge. Here,...

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Main Authors: Guo, Mira T (Author), Briggs, Adrian W (Author), A Weitz, David (Author), Pitkänen, Leena K (Author), Vigneault, Francois (Author), Virta, Marko PJuhani (Author), Spencer, Sarah J. (Contributor), Tamminen, Manu V. (Contributor), Preheim, Sarah P. (Contributor), Brito, Ilana Lauren (Contributor)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Civil and Environmental Engineering (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-04-26T16:09:24Z.
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