Fluorophore-Conjugated Holliday Junctions for Generating Super-Bright Antibodies and Antibody Fragments
The site-specific modification of proteins with fluorophores can render a protein fluorescent without compromising its function. To avoid self-quenching from multiple fluorophores installed in close proximity, we used Holliday junctions to label proteins site-specifically. Holliday junctions enable...
Main Authors: | Theile, Christopher S. (Author), Chen, Guan-Yu (Author), Bilate, Angelina M. (Author), Duarte, Joao N. (Author), Avalos, Ana M. (Author), Fang, Tao (Author), Barberena, Roberto (Author), Sato, Shuji (Author), Ploegh, Hidde (Contributor), Li, Zeyang,S.M.Massachusetts Institute of Technology (Author) |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor) |
Format: | Article |
Language: | English |
Published: |
Wiley Blackwell,
2017-05-01T18:47:33Z.
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Subjects: | |
Online Access: | Get fulltext |
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