Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

Th17 cells are key players in defense against pathogens and maintaining tissue homeostasis, but also act as critical drivers of autoimmune diseases. Based on single-cell RNA-seq profiling of pathogenic versus nonpathogenic Th17 cells, we identified protein C receptor (PROCR) as a cell surface molecu...

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Main Authors: Kishi, Yasuhiro (Author), Kondo, Takaaki (Author), Xiao, Sheng (Author), Yosef, Nir (Author), Gaublomme, Jellert (Author), Wu, Chuan (Author), Wang, Chao (Author), Chihara, Norio (Author), Regev, Aviv (Contributor), Joller, Nicole (Author), Kuchroo, Vijay K. (Author)
Other Authors: Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, The, 2017-05-02T17:41:05Z.
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