RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

RhoA GTPase inhibition organizes contraction during epithelial morphogenesis

During morphogenesis, contraction of the actomyosin cytoskeleton within individual cells drives cell shape changes that fold tissues. Coordination of cytoskeletal contractility is mediated by regulating RhoA GTPase activity. Guanine nucleotide exchange factors (GEFs) activate and GTPase-activating p...

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Bibliographic Details
Main Authors: Mason, Frank M (Contributor), Xie, Shicong (Contributor), Vasquez, Claudia G (Contributor), Martin, Adam C (Contributor), Tworoger, Michael B. (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Tworoger, Michael B (Contributor)
Format: Article
Language:English
Published: Rockefeller University Press, The, 2017-05-02T18:15:11Z.
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