Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients

Preoperative bevacizumab and chemotherapy may benefit a subset of breast cancer (BC) patients. To explore potential mechanisms of this benefit, we conducted a phase II study of neoadjuvant bevacizumab (single dose) followed by combined bevacizumab and adriamycin/cyclophosphamide/paclitaxel chemother...

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Main Authors: Tolaney, Sara M. (Author), Boucher, Yves (Author), Duda, Dan G. (Author), Seano, Giorgio (Author), Ancukiewicz, Marek (Author), Barry, William T. (Author), Goel, Shom (Author), Lahdenrata, Johanna (Author), Isakoff, Steven J. (Author), Yeh, Eren D. (Author), Golshan, Mehra (Author), Brock, Jane (Author), Snuderl, Matija (Author), Winer, Eric P. (Author), Krop, Ian E. (Author), Jain, Rakesh K. (Author), Jain, Saloni R. (Contributor), Martin, John Daniel (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-05-04T22:31:51Z.
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