An extensive allelic series of Drosophila kae1 mutants reveals diverse and tissue-specific requirements for t6A biogenesis
N[superscript 6]-threonylcarbamoyl-adenosine (t6A) is one of the few RNA modifications that is universally present in life. This modification occurs at high frequency at position 37 of most tRNAs that decode ANN codons, and stabilizes cognate anticodon-codon interactions. Nearly all genetic studies...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Cold Spring Harbor Laboratory Press,
2017-05-09T20:54:01Z.
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Subjects: | |
Online Access: | Get fulltext |