Bayesian model reveals latent atrophy factors with dissociable cognitive trajectories in Alzheimer's disease

We used a data-driven Bayesian model to automatically identify distinct latent factors of overlapping atrophy patterns from voxelwise structural MRIs of late-onset Alzheimer's disease (AD) dementia patients. Our approach estimated the extent to which multiple distinct atrophy patterns were expr...

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Bibliographic Details
Main Authors: Zhang, Xiuming (Author), Mormino, Elizabeth C. (Author), Sun, Nanbo (Author), Sperling, Reisa A. (Author), Yeo, B. T. Thomas (Author), Sabuncu, Mert R (Contributor)
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-05-10T19:04:51Z.
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