Controlling uncertainty in aptamer selection

Controlling uncertainty in aptamer selection

The search for high-affinity aptamers for targets such as proteins, small molecules, or cancer cells remains a formidable endeavor. Systematic Evolution of Ligands by EXponential Enrichment (SELEX) offers an iterative process to discover these aptamers through evolutionary selection of high-affinity...

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Main Authors: Spill, Fabian (Contributor), Weinstein, Zohar B. (Author), Irani Shemirani, Atena (Author), Ho, Nga (Author), Desai, Darash (Author), Zaman, Muhammad H. (Author)
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-05-10T19:15:00Z.
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