Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

Emergent rules for codon choice elucidated by editing rare arginine codons in Escherichia coli

The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as noncoding information for gene regulation and genome maintenance. The rare arginine codons AGA and AGG (AGR) present a case study in codon choice, with AGRs encoding important transcriptional and transla...

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Main Authors: Napolitano, Michael G. (Author), Landon, Matthieu (Author), Gregg, Christopher J. (Author), Lajoie, Marc J. (Author), Govindarajan, Lakshmi (Author), Mosberg, Joshua A. (Author), Kuznetsov, Gleb (Author), Vargas-Rodriguez, Oscar (Author), Isaacs, Farren J. (Author), Söll, Dieter (Author), Goodman, Daniel Bryan (Contributor), Church, George M (Contributor)
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science (Contributor), Harvard University- (Contributor)
Format: Article
Language:English
Published: National Academy of Sciences (U.S.), 2017-05-10T19:34:32Z.
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