Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution

Tracing Dynamic Changes of DNA Methylation at Single-Cell Resolution

Mammalian DNA methylation plays an essential role in development. To date, only snapshots of different mouse and human cell types have been generated, providing a static view on DNA methylation. To enable monitoring of methylation status as it changes over time, we establish a reporter of genomic me...

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Bibliographic Details
Main Authors: Stelzer, Yonatan (Author), Soldner, Frank (Author), Markoulaki, Styliani (Author), Shivalila, Chikdu Shakti (Contributor), Jaenisch, Rudolf (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biology (Contributor), Whitehead Institute for Biomedical Research (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-05-11T16:14:03Z.
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