Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning

Living-cell-based screens can facilitate lead discovery of functional therapeutics of interest. A versatile and scalable method is reported that uses dense arrays of nanowells for imparting defined patterns on monolayers of cells. It is shown that this approach can coordinate a multi-component biolo...

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Bibliographic Details
Main Authors: Ozkumur, Ayca Yalcin (Author), Love, John C (Contributor), Goods, Brittany A. (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Department of Chemical Engineering (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Wiley Blackwell, 2017-05-30T19:29:25Z.
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