Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma

Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma

During a survey of clinical rectal prolapse (RP) cases in the mouse population at MIT animal research facilities, a high incidence of RP in the lamellipodin knock-out strain, C57BL/6-Raph1[superscript tm1Fbg] (Lpd[superscript -/-]) was documented. Upon further investigation, the Lpd[superscript -/-]...

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Main Authors: Chen, Xiaowei (Author), Nagar, Karan K. (Author), Wang, Timothy C. (Author), Miller, Cassandra L. (Contributor), Muthupalani, Sureshkumar (Contributor), Shen, Zeli (Contributor), Drees, Frauke (Contributor), Ge, Zhongming (Contributor), Feng, Yan (Contributor), Gong, Guanyu (Contributor), Gertler, Frank (Contributor), Fox, James G (Contributor)
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering (Contributor), Massachusetts Institute of Technology. Division of Comparative Medicine (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor)
Format: Article
Language:English
Published: Public Library of Science, 2017-05-31T13:20:47Z.
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