Virtually Instantaneous, Room-Temperature [[superscript 11]C]-Cyanation Using Biaryl Phosphine Pd(0) Complexes
A new radiosynthetic protocol for the preparation of [[superscript 11]C]aryl nitriles has been developed. This process is based on the direct reaction of in situ prepared L·Pd(Ar)X complexes (L = biaryl phosphine) with [[superscript 11]C]HCN. The strategy is operationally simple, exhibits a remarkab...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS),
2017-06-01T20:21:38Z.
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Subjects: | |
Online Access: | Get fulltext |