Divergent Transcription: A Driving Force for New Gene Origination?

The mammalian genome is extensively transcribed, a large fraction of which is divergent transcription from promoters and enhancers that is tightly coupled with active gene transcription. Here, we propose that divergent transcription may shape the evolution of the genome by new gene origination.

Bibliographic Details
Main Authors: Sharp, Phillip A. (Contributor), Wu, Xuebing, Ph. D. Massachusetts Institute of Technology (Author)
Other Authors: Massachusetts Institute of Technology. Computational and Systems Biology Program (Contributor), Massachusetts Institute of Technology. Department of Biology (Contributor), Koch Institute for Integrative Cancer Research at MIT (Contributor), Wu, Xuebing (Contributor)
Format: Article
Language:English
Published: Elsevier, 2017-06-02T15:35:45Z.
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