MiR-137-derived polygenic risk: effects on cognitive performance in patients with schizophrenia and controls

Variants at microRNA-137 (MIR137), one of the most strongly associated schizophrenia risk loci identified to date, have been associated with poorer cognitive performance. As microRNA-137 is known to regulate the expression of ~1900 other genes, including several that are independently associated wit...

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Main Authors: Cosgrove, D (Author), Harold, D (Author), Mothersill, O (Author), Anney, R (Author), Hill, M J (Author), Bray, N J (Author), Blokland, G (Author), Donnelly, Peter (Author), Bates, Lesley (Author), Barroso, Ines (Author), Blackwell, Jenefer M (Author), Bramon, Elvira (Author), Brown, Matthew A (Author), Casas, Juan P (Author), Corvin, Aiden (Author), Deloukas, Panos (Author), Duncanson, Audrey (Author), Jankowski, Janusz (Author), Markus, Hugh S (Author), Mathew, Christopher G (Author), Palmer, Colin N A (Author), Plomin, Robert (Author), Rautanen, Anna (Author), Sawcer, Stephen J (Author), Trembath, Richard C (Author), Viswanathan, Ananth C (Author), Wood, Nicholas W (Author), Spencer, Chris C A (Author), Band, Gavin (Author), Bellenguez, Céline (Author), Freeman, Colin (Author), Hellenthal, Garrett (Author), Giannoulatou, Eleni (Author), Hopkins, Lucinda (Author), Pirinen, Matti (Author), Pearson, Richard (Author), Strange, Amy (Author), Su, Zhan (Author), Vukcevic, Damjan (Author), Langford, Cordelia (Author), Hunt, Sarah E (Author), Edkins, Sarah (Author), Gwilliam, Rhian (Author), Blackburn, Hannah (Author), Bumpstead, Suzannah J (Author), Dronov, Serge (Author), Gillman, Matthew (Author), Gray, Emma (Author), Hammond, Naomi (Author), Jayakumar, Alagurevathi (Author), McCann, Owen T (Author), Liddle, Jennifer (Author), Potter, Simon C (Author), Ravindrarajah, Radhi (Author), Ricketts, Michelle (Author), Waller, Matthew (Author), Weston, Paul (Author), Widaa, SaraWidaa (Author), Whittaker, Pamela (Author), Richards, A (Author), Mantripragada, K (Author), Owen, M (Author), O'Donovan, M C (Author), Gill, M (Author), Corvin, A (Author), Morris, D W (Author), Donohoe, G (Author), Petryshen, Tracey (Contributor)
Other Authors: Broad Institute of MIT and Harvard (Contributor)
Format: Article
Language:English
Published: Nature Publishing Group, 2017-06-08T17:29:42Z.
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