Strong Enrichment of Aromatic Residues in Binding Sites from a Charge-neutralized Hyperthermostable Sso7d Scaffold Library
The Sso7d protein from the hyperthermophilic archaeon Sulfolobus solfataricus is an attractive binding scaffold because of its small size (7 kDa), high thermal stability (Tm of 98 °C), and absence of cysteines and glycosylation sites. However, as a DNA-binding protein, Sso7d is highly positively cha...
Main Authors: | , , , , , , , , |
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Other Authors: | , , |
Format: | Article |
Language: | English |
Published: |
American Society for Biochemistry and Molecular Biology (ASBMB),
2017-06-13T17:35:49Z.
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Subjects: | |
Online Access: | Get fulltext |